KAROLA MESSNER

Dr.-Karola-Messner-Stiftelse

Pris för idrottsmedicinsk forskning med hög vetenskaplig och etisk kvalitet

·Stiftelsen är grundad av namngivaren 1996 i München, Tyskland. Stiftelsens syfte är att stödja idrottsmedicinsk forskning med hög vetenskaplig och etisk kvalitet.

·Dagens vetenskap påverkas starkt av vinsttänkande från industrin och regeringen, därför finns en ökad trend för snabba, slarvigt genomförda studier med överdriven tolkning av resultaten. Stiftelsen vill uppmuntra forskare som trenden till trots försöker hålla upp kvaliteten och belönar därför forskning med bra vetenskaplig design och en ärlig diskussion av resultatens betydelse.

·I samarbete med professor Michael Kjaer ger Dr. Karola Messner Stiftelsen sedan 2004  ett Messner-pris för den eller de bästa vetenskapliga artiklar publicerade i  SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS.

·De enligt journalens editorer tre till fem bästa artiklar året innan utvärderas av Stiftelsens vetenskapliga kommitté (prof. Jan Gillquist och prof. Karola Messner, Sverige) gällande studiedesign, utförande och resultatdiskussion.  Priset fördelas endast om minst en av de utvärderade artiklarna möter kvalitetskraven. 

·Priset är för närvarande 1.500 Euro för varje artikel och ett diplom.

Previous Price winners and motivations

1999 Jan Friden - Sweden
For his life time research to date

Motivation: Straight forward research to solve the question what happens in patients with muscle sore, later attempt to use obtained knowledge in muscle and tendon transfers. Always careful study design, performance and statistical analysis, critical review of methods and results. 

2001 Mike Benjamin - Great Britain
for his life time research to date

Motivation: The lesson to be learnt from Mike Benjamin is that we should first try to gather as much knowledge in a very broad sense as possible and then ask our question so that it can be answered with a minimum of technical gadgets, not more than necessary for the question at hand. What can be demonstrated by simple observation does not need a more complicated set of methods. 

2004  (best article in Scand J Med Science Sports 2003)
Odd-Egil Olsen, G. Myklebust, L. Engebretsen, I. Holme and R. Bahr (Norway): Relationship between floor type and risk of ACL injury in team handboll.

Motivation: The article has well succeeded to bring forward the subject of floor type and risk for ACL injury in handboll. An article which rather tells about the complexity of the subject than about definitive conclusions.

2005 (best articles in Scand J Med Science Sports 2004)
K.K. Kalliokoski et al. (Finland): Myocardal perfusion after marathon running.

Motivation: The study focuses on a very basic issue concerning physical activity - well founded introduction - aequate material, design and evaluation - thorough discussion - one of the rare studies which make things more clear instead of more confusing.

N. Wedderkopp et al. (Danmark): Secular trends in physical fitness and obesity in Danish 9-year-old girls and boys; Odense School Child Study and Danish substudy and European Youth Heart Study.

Motivation: The study focuses on an issue of overall importance for mankind - high number of cases - relevant comparison by choice of the same geographical region - adequate statistical analysis - good presentation of results - short and balanced discussion without exaggerated conclusions - important article concerning lifestyle and physical activity

2006 (best article in Scand J Med Science Sports 2005)
Kristin Reimers Kardel (Norway): Effects of intense training during and after pregnancy in top-level athletes.

Motivation: The study concerns an important problem i team handball, possibly applicable also to other ball sports - it also addresses gender differences - the material is large enough to demonstrate interesting findings - the presentation of the study is superior - the paper is a good example of a well-performed observational study with extensive and exemplary discussion - the paper could be used as a model for students of scientific methodology.

2007 no winner

2008 (best article in Scand J Med Science Sports 2007)
S.A Anderssen, S. Carroll, P. Urdal, I. Holme (Norway): Combined diet and exercise intervention reverses the metabolic syndrome in middle-aged males: results from the Oslo diet and exercise study.

Motivation: The paper considers a very important question: the relative contributions of life style improvement and diet for reversal of the metabolic syndrome, a combination of several cardiovascular disease risk factors. The background is well described and the authors have performed a well designed, prospective experimental study in human subjects. The numder of included subjects as well as the study period are adequate. The results are analysed with appropriate statistical methods and have great importance. The authors show that a change of diet and an increase in physical activity have separate effects in diminishing the prevalence of the metabolic syndrome and that the effect of a combination of the two interventions is additive. The discussion of results is well written and balanced.

Support of the 7th Bispejerg Symposium on Sports Medicine

The foundation supports the participation of prof. Mike Benjamin and Prof Karl Kadler at the symposium for their important research on a high sound ethical basis in the field of Sports Medicine.

2009 (best article in Scand J Med Science Sports 2008)
B. Wolfarth et al. (Germany): Endothelial nitric oxide synthase gene polymorphism and elite endurance athlete status: the Genathlete study.
Motivation: A well designed descriptive study in human subjects from a wide geographical area with possibility to generalise the findings.

2010 (best articles in Scand J Med Science Sports 2009)
T. Starborg, Y. Lu, A. Holmes, K. E. Kadler (UK): Electron microscope 3D reconstruction of branched collagen fibrils in vivo
Motivation: A marvelous exampel how clear, straightforward and beautiful descriptive research can be, provided that the scientist masters his techniques.

M. Kongsgaard et al. (Denmark): Corticosteroid injections, eccentric decline squat training and heavy slow resistance training in patellar tendinopathy
Motivation: A randomized clinical investigation, conducted according to all rules of good science, which could serve as example for how the effectiveness of clinical treatment should be tested.

Sammanfattning av Karola Messners naturvetenskapliga forskning

Forskning inom biologi och medicin har olika inriktningar 1) att undersöka kroppsfunktionernas normaltillstånd och avvikelser för att skapa en kunskapsbas, 2) att utveckla behandlingar och 3) att testa behandlingar. Karola Messners huvudämne var ledbrosk, hur ledbrosk fungerar under utveckling och belastning och hur det påverkas av olika skador och behandlingar. Ligament-, menisk- och broskskador i knäleden är mycket vanliga inom idrotten. Moderna cellodlingstekniker och tillförsel av bioaktiva substanser har ansetts revolutionerande inom behandlingen.  Karola Messners forskning visade att skador på ligament och menisk leder till sekundära broskskador i knäleden, som inte kan avhjälpas med de mest moderna tekniker för rekonstruktion och läkning. Problemet ligger i den särskilda fysiologin av dessa högt belastade vävnader. 

75 originalartiklar publicerade i bland andra: American Journal of Sports Medicine, Clinical Biomechanics, Clinical Orthopedics, Acta Orthopaedica Scandinavica, Journal of Biomedical Materials Research, Biomaterials, Journal of Anatomy, Journal of Anatomy and Embryology, Acta Radiologica, Acta Anatomica, Osteoarthritis and Cartilage, Journal of Cells, Tissues, Organs, Scandinavian Journal of Medicine and Science in Sports, och fler (för närmare informationan se MEDLINE ).

18 översiktsartiklar och bokkapitel, och över 60 olika abstrakt.